「ぶつけた覚えもないのに青あざがで
きる」「歯を磨くと出血しやすい」といった症状が出たり、「健康診断で血小板が少ないと言われた」という人は特発性血小板減少性紫斑病の疑いがある。出血
を止める働きをする血小板に対する自己抗体ができ、破壊されるために減少するという。
日本には約二万人の患者がいる。子どもだけでなく大人にも多い。女性の患者が男性の三倍という統計もある。慶応大学の池田康夫教授は「血小板が減る病気は多いので、まず専門医に正確な診断をつけてもらうのが重要」と指摘する。
診断が確定したら、副腎皮質ステロイドなどの薬で治療していく。子どもの場合は急性型のことも多く、自然に治癒するという。最近では胃がんなどとの関連性
が強いとされる「ヘリコバクターピロリ菌」に感染しているかどうかを検査し、除菌すると効果があることもわかってきた。
細かい仕組みは研究中だが、「もし陽性なら除菌するのがいい。除菌によって半数以上の患者で血小板数が増え、完全に正常数になる人もいる」（池田教授）という。
特発性血小板減少性紫斑病の主な症状
- 点状や斑状の皮膚内出血
- 歯茎からの出血
- 鼻血
- 便に血が混じったり、黒い便が出たりする
- 尿に血が混じり紅茶のような色になる
- 月経過多
- 重症な場合は脳出血
（注）難病情報センターの資料をもとに作成
引用元：2008年12月7日 日経新聞SUNDAY NIKKEI「１分間人間ドック」より
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